Clinical Findings and Dental Manifestations Associated With Microcephalic Osteodysplastic Primordial Dwarfism Type II: A Case Report

Background: Microcephalic Osteodysplastic Primordial Dwarfism type 2 (MOPD II) is a rare untreatable genetic disorder characterized by severe prenatal and postnatal growth retardation, microcephaly, bird-headed face (receding forehead chin, beaklike nose, prominent eyes), skeletal abnormalities, abnormal dentition, hair skin changes, high-pitched nasal voice, an increased risk for insulin resistance cerebrovascular disease. MOPDII caused mutations in the pericentrin gene inherited autosomal recessive manner. This study aims to report MOPD II child patient. Case Presentation: A seven-year-old girl genetically diagnosed with has been presented this case report. Clinical, radiological, laboratory findings emphasis on oral features have reported, her dental problems management also described. Conclusions: patients shorter life expectancy. The main health complications which need regular care include vascular changes of central nervous system, diabetes mellitus, renal problems, blood pressure, cardiac pathologies, hematologic profile. high caries because they consume soft cariogenic foods due microdontia, oligodontia, incompetent masticatory system. On other hand, treatment such can be very challenging. cases their families should aware importance hygiene routine follow-ups.